Photodynamic Therapy-Induced Immune Modulation: Part III

Exclusion Criteria

• •PDT on less than 5% body surface area (eg, forehead)
• •Present treatment with corticosteroids or Non-steroidal inflammatory drugs (e.g., cyclooxygenase inhibitors) within past 2 months (except low-dose 81 mg aspirin).
• •On antioxidant supplements (e.g., vitamin C) for past 2 months
• •Tanning bed use within last 3 months
• •PDT treatments within last 3 months
• •Significant health issues that could affect the immune system (e.g., uncontrolled Diabetes Mellitus, Rheumatoid arthritis, skin rashes, psoriasis) that could interfere with testing
• •Pregnant or nursing
• •No immunosuppression, and on no immunosuppressive medications or NSAIDS within past 30 days (except low-dose \[81 mg daily\] aspirin).
• •No significant underlying diseases that could potentially interfere with the immune assays or cardiac or renal or liver problems.
• •History of blood clot or hypercoagulable state or GI bleed/ulceration.