The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans

Inclusion Criteria

• •Adult Males and Females ages 18 and older who are patients at the Dayton VAMC Dermatology clinics
• •Skin type must be "Fair", Fitzpatrick type I or II, due to the presence of actinic damage in this population.
• •Subjects must have a VA physician's order to receive PDT treatment on their forearms.
• •Willing to participate and understand the informed consent document.
• •Willing to avoid excess sun exposure/tanning beds to the area to be treated with PDT.
• •Has stable transportation to attend study visits at DVA