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Randomized Control Trial of Staged Versus Simultaneous Bilateral Total Knee Arthroplasty
The purpose of this study is to assist surgeons and patients in answering the question "Should I have both knees replaced at the same time, or should I just do one and wait to do the second one?"
This is a multi-center randomized controlled trial of 224 patients in order to clearly delineate differences in post-operative outcomes and the trajectory of recovery between simultaneous and staged bilateral KA. The primary outcome measure is difference in generic health related quality of life between the two groups measured 1 year following surgery. Secondary outcome measures include differences in joint specific scores, time off work, satisfaction and costs. This trial will inform patients and clinicians about differences in recovery, function and efficacy of the procedure to aid in the selection of treatment pathway to best suit the patient.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
University of Calgary
Calgary, Alberta, Canada
Concordia Hospital
Winnipeg, Manitoba, Canada
St. Joseph's - McMaster University
Hamilton, Ontario, Canada
Kingston Health Sciences Center - KGH
Kingston, Ontario, Canada
London Health Sciences Centre
London, Ontario, Canada
Ottawa Hospital Research Institute
Ottawa, Ontario, Canada
St. Michael's Hospital
Toronto, Ontario, Canada
McGill University
Montreal, Quebec, Canada
Start Date
March 19, 2018
Primary Completion Date
April 1, 2026
Completion Date
December 1, 2026
Last Updated
February 20, 2026
224
ESTIMATED participants
Simultaneous Knee Arthroplasty (UKA)
PROCEDURE
Staged Knee Arthroplasty (UKA)
PROCEDURE
Lead Sponsor
Orthopaedic Innovation Centre
NCT07351968
NCT06747494
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06906939