Sleep and Circadian Mechanisms of Non-dipping Blood Pressure

Exclusion Criteria

• •Currently treated with pharmacologic agents for hypertension
• •Blood pressure \>160/100 mmHg
• •Smoked within the last year
• •Regular night work or rotating shift work for the three months prior to the study
• •Travel across more than three time zones during the three months prior to the study.
• •Any acute, chronic or debilitating medical conditions, other than mild hypertension (140\<SBP\<160 or 90\<DBP\<100 mmHg) and severe renal disease (glomerular filtration rate \<30)
• •Moderate to severe obstructive sleep apnea (OSA)
• •History of severe psychiatric illnesses or psychiatric disorders will be excluded, including alcoholism, drug dependency, major depression, manic depressive illness, schizophrenic disorders, panic disorder, generalized anxiety disorder, post-traumatic stress disorder, agoraphobia, claustrophobia, paranoid personality disorder, schizoid personality disorder, schizotypal personality disorder, borderline personality disorder, and antisocial personality disorder.