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Bariatric Surgery and Pharmacokinetics Methylphenidate: BAR-MEDS Methylphenidate
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study we investigate the pharmacokinetic effects of bariatric surgery on methylphenidate.
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
No
St. Olavs University Hospital
Trondheim, Norway
Start Date
January 2, 2018
Primary Completion Date
June 25, 2021
Completion Date
June 25, 2021
Last Updated
June 27, 2025
1
ACTUAL participants
Methylphenidate
DRUG
Lead Sponsor
Norwegian University of Science and Technology
Collaborators
NCT03868592
NCT05242835
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT05918575