The Effects of Hesperidin on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease

Exclusion Criteria

• •Diabetes
• •Taking any kind of antibiotics two weeks before recruitment
• •History of alcohol consumption
• •pregnancy or lactation
• •Professional athletes
• •Other liver disease (viral/etc)
• •Use of drugs such as calcium channel blockers, high dose synthetic estrogens, methotrexate , amiodarone, steroids, chloroquine, immunosuppressive drugs, lipid-lowering agents, metformin and vitamin E
• •A history of Hypertension, Cardiovascular disease, Pulmonary disease, Renal disease \& Celiac disease; Cirrhosis
• •History of Upper GI surgery / Prior surgical procedures such as jejunoileal or jejunocolic bypass, gastroplasty
• •Following program to lose weight in recent 3 mo
• •A history of hypothyroidism or Cushing's syndrome