Biological Dating of Cerebral Ischemia With GST-π/PRDX1 to Detect Patients With Stroke of Unknown Onset Within the Therapeutic Window of Thrombolysis

Inclusion Criteria

• •Patients over 18 years old
• •Patients with symptoms consistent with stroke and a National Institute of Health Stroke Score ≥3 at the inclusion time
• •Time symptom onset ≤ 24 hours at inclusion:
• •* For patients with time of symptom onset is \<4.5h at inclusion, the time of symptom onset has to be precisely known, with a margin of error not exceeding 30 minutes (through patient or witness interview)
• •* For patients with time of symptom onset is \>4.5h at inclusion, knowledge of precise time of symptom onset is not required. For these patients, to ensure onset-to-inclusion time is between 4.5 and 24 hours at inclusion:
• •last time patient presented no deficit must be less than 24 hours,
• •symptoms must have been first recognized more than 4.5 hours before blood draw.
• •Possibility to perform MRI within the 30 minutes following blood collection
• •Person affiliated to or beneficiary of a social security plan