Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Oxford
With
King's College London
Oxford University Hospitals NHS Trust
University of Southampton
University of Birmingham
Barts & The London NHS Trust
City, University of London
National Institute for Health Research, United Kingdom
BUMP 1 will randomise 2262 women at higher risk of hypertension in pregnancy into usual care or self-monitoring.
BUMP 2 will randomise 512 women with hypertension in pregnancy (including chronic hypertension) into usual care or self-monitoring. Women in BUMP 1 will move into BUMP 2 if they develop hypertension.
Women will be recruited at approximately 15 hospitals in England over approximately 24 months.
Women will be recruited from 20 weeks (BUMP 1) or early pregnancy(BUMP 2) and followed up until 2 months after birth.
Age
18–any
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
BUMP 1
Participant is willing and able to give informed consent for participation in the trial
Pregnant woman, aged 18 years or above between 16+0 to 24+0 weeks
Able and willing to comply with trial requirements
Willing to allow her general practitioner and consultant, if appropriate, to be notified of participation in the trial
At higher risk for hypertension in pregnancy / pre-eclampsia defined as one or more of the following risk factors:
Age 40 years or older
Nulliparity
Pregnancy interval of more than 10 years
Family history of pre-eclampsia
Previous history of pre-eclampsia or gestational hypertension
Body mass index 30 kg/m2 or above at booking
Chronic kidney disease
Twin pregnancy
Diabetes (Type 1\&2)
Autoimmune Disease (eg systemic lupus erythematosis or antiphospholipid disease)
Women developing pregnancy hypertension previously randomised in BUMP 1 (regardless of gestation).
OR
Women with chronic hypertension (defined as sustained systolic BP≥140 mmHg and/or diastolic BP≥90 mmHg, present at booking or before 20 weeks' gestation, or receiving treatment outside pregnancy and/or at time of referral).
Recruited up to 37+0 weeks' gestation.
OR
Women with hypertension after 20 weeks' gestation (defined as sustained systolic BP≥140 mmHg and/or diastolic BP≥90 mmHg).
Recruited at 20+0 to 37+0 weeks' gestation.
AND
Participant is willing and able to give informed consent for participation in the trial.
Woman aged 18 years or above.
Willing to allow her general practitioner and consultant, if appropriate, to be notified of participation in the trial.
You may not be if
Chronic Hypertension
BUMP 2:
Anticipated inpatient admission considered likely to lead to imminent delivery (within the next 48 hours)
Clareo Health | Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension
