Lead Sponsor

Samsung Medical Center

Age

20 - 70 years

Sex

FEMALE

Healthy Volunteers

Yes

•histologically confirmed cervical cancer
•radical hysterectomy and pelvic lymph node dissection was done
•histologically indicated adjuvant radiotherapy ( more than one as below)
•1. tumor size ≥4 cm
•2. positive lymphovascular invasion
•3. more than half stromal invasion depth
•ECOG performance status 0 or 1
•Bone marrow function: granulocyte ≥1.0 x 1000/µl, platelet ≥30 x 1000/µl, hemoglobin ≥10 g/dl

•positive pelvic lymph node metastasis
•positive distant metastasis (including retroperitoneal lymph node metastasis)
•positive tumor involvement on resection margin
•positive parametrial invasion
•previous history of pelvic radiotherapy
•more than 3 months after radical surgery for cervical cancer
•neoadjuvant chemotherapy was done
•previous history of other carcinoma except for thyroid cancer, skin cancer, in situ carcinoma on cervix