Lead Sponsor

Antiva Biosciences

Age

25 - 50 years

Sex

FEMALE

Healthy Volunteers

No

•Women, 25 to 50 years old.
•Cervical HSIL diagnosis made within 2 months of enrollment and confirmed with biopsy with no evidence of invasive cancer in any specimen and must be p16+.
•Able and willing to abstain from sexual intercourse for 48 hours prior to first dose and 2 days after each dose.
•Generally experiencing regular menstrual cycles, unless using long-acting reversible contraception that induces amenorrhea (e.g., Mirena IUD, Norplant).

•Women who are pregnant, plan to become pregnant in the next 4 months, or lactating females.
•History of cancer, except basal cell or squamous cell carcinoma of the skin.
•History of genital herpes with \> 3 outbreaks per year, or active non-HPV vaginal infection.
•Plan to have excision or ablation of the lesion(s) within 3 months of enrollment.
•History of cervical cancer, colposcopy suspicious for cancer, any prior treatment of CIN, or hysterectomy.