WITHDRAWNPHASE4

Effect of Mechanical Loading With PTH on Cortical Bone

NCT03232476•Massachusetts General Hospital

Summary

Clinical trial to investigate effect of voluntary upper extremity loading in combination with anabolic osteoporosis therapy.

Eligibility

Age

45 - No limit years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•women aged 45+
•postmenopausal
•osteoporotic with high risk of fracture

Exclusion Criteria

•no significant previous use of bone health modifying treatments

Key Dates

Start Date

July 1, 2017

Primary Completion Date

December 1, 2019

Completion Date

December 1, 2019

Last Updated

November 25, 2025

Conditions

Osteoporosis, Postmenopausal

Interventions

Upper extremity voluntary loading

DEVICE

Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study)

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RECRUITINGNA

Vascular Function, Sarcopenia and Pain in Postmenopausal Osteoporosis

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COMPLETEDPHASE3

A Comparison Study With Alendronate and Raloxifene in Postmenopausal Women With Osteoporosis (0217-189)

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 25, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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COMPLETEDPHASE4