Clareo Health | Ciliation and Mucus Rheology Parameters Determined Via Air-liquid-interface Cell Cultures in Non-smoking, Smoking, COPD and Asthmatic Patients
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Montpellier
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
The subject has given free and informed consent and signed the consent form
The subject is affiliated with or beneficiary of a medical insurance program
The subject has never smoked
No obstructive breathing disorder (forced expiratory volume at one second (FEV1) \>70% of predicted value; the ratio of FEV1 to forced vital capacity (FEV1/FVC) is \> 0.7)
No known respiratory disease
The subject has given free and informed consent and signed the consent form
The subject is affiliated with or beneficiary of a medical insurance program
Smoker or former smoker (\>= 30 pack years)
No obstructive breathing disorder (forced expiratory volume at one second (FEV1) \>70% of predicted value; the ratio of FEV1 to forced vital capacity (FEV1/FVC) is \> 0.7)
The subject has given free and informed consent and signed the consent form
The subject is affiliated with or beneficiary of a medical insurance program
Smoker or former smoker (\>= 30 pack years)
Subject presenting with COPD: FEV1/FVC \< 0.7 (based on spirometry values in the medical file and performed in the 3 months prior to inclusion)
The subject requires bronchial fibroscopy (decision made by pneumologist)
COPD of grade "2" or "3" according to GOLD criteria (Global Initiative for Chronic Obstructive Lung Disease)
The subject has given free and informed consent and signed the consent form
The subject is affiliated with or beneficiary of a medical insurance program
Non-smoker or former smoker (\<10 pack years)
Subject presenting with severe asthma: FEV1/FVC \>= 0.7 and FEV1 \< 80%
The subjects requires bronchial fibroscopy (decision made by pneumologist)
You may not be if
The subject has an extensive neoplastic disease
The subject has another active lung disease (tuberculosis, pulmonary interstitium disease, active or recent pulmonary infection)
The subject has had a recent psychiatric disorder (within one year prior to inclusion and documented by a specialist consultation)
Emergency situations (object extractions...)
Subject consuming illicit drugs or alcohol
The subject is in an exclusion period determined by a previous study
The subject is under judicial protection, or is an adult under any kind of guardianship
