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Pilot Study of the Tolerability of Nivolumab for Relapsed or Residual Haematological Malignancies After Allogeneic Haematopoietic Stem Cell Transplantation
This is a prospective study of the safety and efficacy of nivolumab for the treatment of relapsed or residual haematological malignancies after allogeneic stem cell transplantation (alloSCT). Eligible patients will receive nivolumab at a dose of 3mg/kg intravenously every 2 weeks. The primary objective is to evaluate the incidence, severity and treatment responsiveness of GVHD following nivolumab treatment post-alloSCT.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Royal Melbourne Hospital
Parkville, Victoria, Australia
Start Date
May 8, 2017
Primary Completion Date
March 1, 2022
Completion Date
March 1, 2022
Last Updated
September 23, 2021
14
ESTIMATED participants
Nivolumab Injection
DRUG
Lead Sponsor
Melbourne Health
NCT04068597
NCT06510699
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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