Intracellular Phosphate Concentration Evolution During Hemodialysis by MR Spectroscopy

Exclusion Criteria

• •Major subject protected by law
• •Prisoners or subjects who are involuntarily incarcerated
• •Denutrition (weight loss ≥ 5 kg in one months/10 kg in 6 months, Body Mass Index (BMI) ≤ 21 kg/m2, albuminemia ≤ 35 g/L)
• •Obesity (BMI ≥ 30 kg/m2)
• •Phosphatemia at the start of the dialysis \< 1,5 mmol/L or \> 3 mmol/L
• •Secondary hyperparathyroidism with parathormone (PTH) ≥ 1000 pg/mL
• •Adynamic osteopathy (PTH ≤ 50 pg/mL)
• •Hypoparathyroidism with a history of parathyroidectomy
• •Hemoglobin ≤ 100 g/L
• •Contraindication to heparin
• •Temporary vascular access
• •Contraindication to resonance magnetic spectroscopy (pacemaker or insulin pump, metallic valvular prosthesis, valvular prosthesis not compatible with resonance magnetic spectroscopy, dental appliance, intracerebral clip, claustrophobic subject).
• •Simultaneous participation to another research protocol
• •Patient not affiliated to a social security system