Magnesium Supplementation for Primary Prevention of Heart Failure in Obesity

Exclusion Criteria

• •1. History of hospitalization for heart failure (systolic or diastolic);
• •2. Unstable angina or prior myocardial infarction;
• •3. LV ejection fraction \<50% on imaging study;
• •4. Valvular heart disease (stenosis or insufficiency) greater than moderate degree;
• •5. Renal dysfunction, serum creatinine \>2.5 mg/dL or estimated creatinine clearance \<30 mL/min/1.73 m2 (30),
• •6. Pregnant women or actively breastfeeding women
• •7. History of drug supplementation within the last 6 months in which more than 50 miliequivalents per day of supplemental magnesium is contained