Joint Pain Occurring During Anti-TNF Therapy in Chronic Inflammatory Bowel Disease

NCT02899871•Centre Hospitalier Universitaire, Amiens

Summary

IBD (inflammatory bowel disease) are associated with various types of joint manifestations, especially inflammatory. Patients with IBD treated with anti-TNF commonly report joint symptoms, with variable expressions and aetiologies, possibly responsible for impaired quality of life, and possibly leading to discontinuation of an effective and validated treatment.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Males or females over the age of 18 years at the time of inclusion
•Patients with IBD (Crohn's disease or ulcerative colitis), diagnosed by a set of compatible clinical (chronic diarrhoea, haematochezia, anoperineal lesions, etc.), laboratory, histological and endoscopic arguments. Patients will be included regardless of the severity of their disease, its clinical course, the type of lesions, and the presence or absence of associated manifestations.
•Patients treated with anti-TNF: infliximab or adalimumab.
•Informed patients not refusing to participate.
•Patients covered by French national health insurance.

Exclusion Criteria

•Patients under the age of 18 years at the time of inclusion.
•Patients previously treated with anti-TNF, but no longer treated with anti-TNF at the time of inclusion.
•Protected majors (under permanent or temporary guardianship).

Locations (1)

CHU Amiens

Amiens, France

Key Dates

Start Date

September 1, 2014

Primary Completion Date

September 1, 2016

Completion Date

October 1, 2016

Last Updated

August 10, 2018

Enrollment

ACTUAL participants

Conditions

Inflammatory Bowel Diseases

Interventions

diagnosis of joint

OTHER

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

NCT06226883

Inflammatory Bowel DiseasesCrohn's Disease

View study

RECRUITING

Institutional Registry of Rare Diseases

NCT06573723

Rare DiseasesAmyloidosis+24 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 10, 2018Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Joint Pain Occurring During Anti-TNF Therapy in Chronic Inflammatory Bowel Disease

Inclusion Criteria

Exclusion Criteria

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Institutional Registry of Rare Diseases

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