Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators

Caregiver will be consented for his/her and the child's participation. The child will assent to participate before study procedures begin. The proposed study will last 52 weeks and consist of study visits every 4 weeks (14 visits total). Screening (roughly 5 mins): 2 item Self-Report Screening Tool for Depression (2-SRSD) This tool will be used to help screen caregivers for the study. This screening will only be performed in the clinic. Additional screening will be performed at the Baseline visit including: * Obtaining demographic information * Physical exam, * Medical and psychiatric history * Physical health assessments * Urine Pregnancy Test for women of childbearing potential * Mood assessments The baseline visit is described below: Baseline (approx 3 hrs): The following assessments will be given to the Caregiver only: 1. Structured Clinical Interview for DSM V (SCID) 2. Urine Pregnancy Test (UPT) for women of child bearing potential 3. Hamilton Rating Scale for Depression (HRSD) 4. Quick Inventory of Depressive Symptomatology Self Report (QIDS-SR) 5. State Trait Anxiety Inventory (STAI) 6. Pediatric Asthma Caregiver's Quality of Life Questionnaire (PACQOL) 7. Psychobiology of Recovery in Depression III Somatic Symptom Scale (PRD-III) The following assessments will be given to the child: 1. Composite Asthma Severity Index (CASI) 2. Children's Depression Inventory (CDI) 3. Screen for Child Anxiety Related Disorders (SCARED) 4. Pediatric Asthma Quality of life Questionnaire (PAQOL) 5. Asthma Control Test/Childhood Asthma Control Test (ACT/cACT) (which version is given will be determined by the child's age) 6. Spirometry measurement 7. Perceived Stress Scale (PSS) 8. Relatedness Scale The following assessments will be given to both the caregiver AND the child: 1\. Childhood Asthma Management Program Continuation Study Medication Adherence Interview (CAMPCS) Weeks 4-48 (visits every 4 weeks, each approx 2 hours): Caregiver only: HRSD, QIDS-SR, STAI, PACQOL, PRD-III, UPT Child only: CASI, CDI, SCARED, PAQOL, ACT/cACT, Spirometry, PSS, Relatedness Scale Both caregiver AND child: CAMPCS Week 52 (approx 2.5 hrs): Caregiver only: HRSD, QIDS-SR, STAI, PACQOL, PRD-III, UPT Child only: CASI, CDI, SCARED, PAQOL, ACT/cACT, Spirometry, PSS, Relatedness Scale Both caregiver AND child: CAMPCS, Debriefing interview Electrocardiograms (ECG) and blood tests may be collected during this study as is clinically indicated.