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This is a randomized controlled pilot study to assess the microbiological and clinical impacts of Fecal Microbiota Transplantation (FMT) in patients with obesity. The investigators will prospectively enroll 20 adult patients who are obese (Body Mass Index of 35kg/m2 or higher) after providing written informed consent. The study participants will be randomized 1:1 to either the treatment arm or the placebo arm. The treatment arm will receive an induction FMT with capsules followed by a monthly maintenance dose of oral capsules for 12 weeks total. The placebo group will receive a placebo capsules for induction followed by monthly intake of oral placebo capsules for 12 weeks.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Brigham and Women's Hospital
Boston, Massachusetts, United States
Start Date
April 1, 2017
Primary Completion Date
October 18, 2018
Completion Date
July 24, 2019
Last Updated
January 7, 2020
22
ACTUAL participants
Fecal Microbiota Transplantation
BIOLOGICAL
Placebo
OTHER
Lead Sponsor
Brigham and Women's Hospital
NCT07472881
NCT01143454
Data Source & Attribution
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