Validation Study on the Impact of Decipher® Testing - VANDAAM Study

Inclusion Criteria

• •Adult patients with Karnofsky Performance Status \>70
• •Eastern Cooperative Oncology Group (ECOG) Performance Status 0-1
• •Pathologically (histologically) proven diagnosis of prostate cancer (PCa) undergoing their first line of treatment
• •Meet National Comprehensive Cancer Network (NCCN) criteria for either: Low risk PCa (defined as Gleason score 6 in ≥ 3 cores; T-stage T1c- T2a); Intermediate risk PCa (defined as Gleason score 7, or prostatic specific antigen (PSA) ≥ 10 ng/ml \& \< 20 ng/ml, or T-stage ≤ T2c)
• •Eligible for either radical prostatectomy (RP) or definitive radiation therapy (RT) (+/- short-term androgen deprivation therapy (ADT))
• •Age \> 18 years
• •Biopsy specimen available