Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Zhi Yang
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Relapsed or refractory HER2 positive cancer.
2. KPS\>60.
3. Life expectancy\>3 months.
4. Gender unlimited, age from 18 years to 80 years.
5. Assessable lesions with a minimum size of 10mm by CT scan or MRI.
6. Acceptable organ function
Hematology:
* Absolute neutrophil count greater than 800/mm\^3 without the support of filgrastim.
* White blood cell (WBC) (\> 2000/mm\^3).
* Platelet count greater than 50,000/mm\^3.
* Hemoglobin greater than 9.0 g/dl.
Chemistry:
* Serum alanine aminotransferase (ALT)/aspartate aminotransferase (AST) less or equal to 3 times the upper limit of normal (patients without liver metastasis) or 6 times the upper limit of normal (patients with liver metastasis).
* Serum creatinine less or equal to 3 times the upper limit of normal
* Total bilirubin less than or equal to 3 times the upper limit of normal.
7. No other serious diseases(autoimmune disease, immunodeficiency etc.).
8. Adequate cardiac function(LVEF≥40%).
9. No other tumors.
10. Patients volunteer to participate in the research.
You may not be if
1. Allergic to cytokines.
2. Uncontrolled active infection.
3. Acute or chronic GVHD.
4. MODS.
5. Treated with T cell inhibitor.
6. HIV affected.
7. Other situations improper for the research.
Clareo Health | A Clinical Research of CAR T Cells Targeting HER2 Positive Cancer
