Lead Sponsor

Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina

Collaborators

Age

30 - 80 years

Sex

ALL

Healthy Volunteers

No

•Diagnosis of Type 2 DM according to criteria of the World Health Organisation of one or more years of disease duration.
•Age from 30 to 80 years.
•HbA1C ≥ 9% (DCCT) according to the last blood test carried out during the 12 months prior to inclusion in the study
•No changes in the treatment that can influence the main variable during the 3 months prior inclusion in the study.
•Accepting to participate in the study and signing of the informed consent form.

•Patient refuses to participate and any other condition that prevents signing the informed consent form.
•Other types of diabetes: Type 1 DM, gestational diabetes and diabetes secondary to other diseases.
•Pharmacological treatments that interfere with carbohydrate metabolism, such as steroids.
•Life expectancy under 2 years.
•Current treatment for cancer other than basocellular or epidermoid skin cancer.
•Severe mental disease and dementia.
•Heart failure Class III or IV (NYHA).
•Renal transplant or current treatment with dialysis.
•Alcohol and drug abuse.
•Pregnancy or intention to get pregnant.
•Breastfeeding.
•Chronic treatment with steroids; treatment with steroids during the 2 months prior inclusion in the study.
•Pharmacological treatment for weight loss during the 2 months prior to inclusion in the - study.
•Treatment with immunosuppressants.
•Haemoglobinopathies and chronic anaemia.
•Body Mass Index \> 45 mg/kg2 (1)
•Participation in clinical trials for medicines.
•Patients with conditions that prevent follow up and completion of protocol.