Integrated Care for Patients With High Risk Substance Use and Psychiatric Disorder With Chronic Direct Acting Antiviral Treatment

Inclusion Criteria

• •Patients with HCV infection who were referred to the VA HCV clinic and who received the usual initial evaluation in the clinic
• •All patients 18 and 75 years old with confirmed HCV infection
• •Patients were required to be classified as "high risk candidates for antiviral treatment" on any one of a set of screening measure in order to participate
• •Screening measures and cutoffs for inclusion were depression:
• •* Beck Depression Inventory: (BDI) \> 10
• •* Alcohol use: Alcohol Use Disorders Identification Test (AUDIT-C) \> 4
• •* PTSD: VA Primary Care PTSD Screen = endorsement of three or more items or any single endorsement of item #3
• •* Drug use: Drug Use Questionnaire = self-reported drug/alcohol use within 6 months prior to screen