Safety and Efficacy of Acarbose+Saxagliptin Compared With Metformin+Saxagliptin in Patients With Type 2 Diabetes

Exclusion Criteria

• •New or worsening signs or symptoms of coronary heart disease
• •Medical history of active liver disease and kidney disease
• •Poorly controlled hypertension（systolic blood pressure\>160mmHg or diastolic blood pressure\>95mmHg）
• •A clinically important hematological disorder
• •A history of intolerance or hypersensitivity or any contraindication to study medications (including saxagliptin, metformin, acarbose)
• •Is pregnant or breast feeding or is expecting to conceive or donate eggs
• •A medical history of drug abuse
• •Can not be followed -up on time
• •Endocrinological diseases（eg： hyperthyroidism、hypothyroidisn and cushing syndrom）
• •Gastrointestinal diseases
• •Mental disorser
• •Hypoxic disease