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COMPLETEDPhase 2

Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer

A Phase 2 Multicenter, Randomized, Placebo Controlled, Double Blind Study to Assess the Safety and Efficacy of CC-486 (Oral Azacitidine) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Plus Placebo in Subjects With Previously Treated Locally Advanced or Metastatic Non-small Cell Lung Cancer

NCT02546986•Celgene

View on ClinicalTrials.gov

AI summary by Clareo Health

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Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

CC-486

Pembrolizumab

+1 more

Locations

33

United States

Locations (33)

Palo Verde Hematology Oncology

Glendale, Arizona, United States

UCLA Hematology Oncology

Los Angeles, California, United States

Georgetown University Medical Center

Washington D.C., District of Columbia, United States

University Cancer and Blood Center, LLC

Athens, Georgia, United States

Research Medical Center

Kansas City, Missouri, United States

Washington Univ School of Medicine

St Louis, Missouri, United States

Key Dates

Start Date

October 9, 2015

Primary Completion Date

April 13, 2017

Completion Date

July 7, 2025

Last Updated

August 8, 2025

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Sponsors

Lead Sponsor

Celgene

Detailed Description

Full Eligibility Criteria

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 8, 2025Data synced to Clareo: April 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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