Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Strasbourg, France
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18-65 years
Asthma which requires treatment with guidelines suggested medications for GINA steps 4-5
Four or more bursts of systemic corticosteroids \>3 days each in the previous year
Willingness and ability to give written informed consent
You may not be if
Current smoker and former smoker \> 10 pack years total smoking history
Participation in another clinical trial within the prior 4 months
Omalizumab therapy within the prior 4 months
Allergic bronchopulmonary aspergillosis
Patient having had severe exacerbation of their asthma requiring high doses of oral corticosteroids (\> 60 mg equivalent prednisolone) more than one month in the previous year
Post-bronchodilator FEV1 of less than 30%
Past diagnosis of COPD and chronic respiratory insufficiency
Known coagulopathy or platelet dysfunction
Use of anticoagulants
Use of an internal or external pacemaker or internal cardiac defibrillator
Contraindication to perform bronchoscopy
Contraindication to perform general anesthesia
Significant cardiovascular disease
Current or recent respiratory tract infection resolved less than 4 weeks
Known cancer or cancer history less than 12 months
Pregnancy and nursing mother
Clareo Health | Bronchial Thermoplasty in Severe Asthma With Frequent Exacerbations
