Study to Assess Long-Term Outcomes of Trientine in Wilson Disease Patients Withdrawn From Therapy With d-Penicillamine

Inclusion Criteria

• •Patients aged 1 year to 90 years of age.
• •Physician established diagnosis of Wilson disease based on a Ferenci score \> 3.
• •Documented treatment with d-Penicillamine, withdrawal of treatment with d- Penicillamine, followed by treatment with trientine for at least 6 months at date of informed consent.
• •Able/willing to provide written informed consent.
• •For enrolment in the prospective part, enrolment in the retrospective part of the study is required.