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The Exploratory Handheld Optical Coherence Tomography Study in Wilson's Disease

Developing a Handheld Anterior Segment Optical Coherence Tomography Device to Assess Kayser Fleischer Rings in Wilson's Disease

NCT07046507•Royal Surrey County Hospital NHS Foundation Trust

View on ClinicalTrials.gov

Summary

This is an exploratory study using anterior segment optical coherence tomography (OCT) devices to measure copper in the eye. The investigators hope to use this to diagnosis kayser flesicher rings, an important diagnostic criteria in Wilson's disease.

Eligibility

Age

18 - 90 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Wilson patients with Kayser Fleischer rings on slit lamp examination and 5 patients without Kayser Fleischer rings on slit lamp examination

Exclusion Criteria

•Those who do not have a confirmed diagnosis of Wilson's disease and no previous formal slit lamp examination will be excluded from recruitment.
•The investigators will also exclude those patients with known corneal disease, history of intraocular disease, haematological disease, pregnancy, and use of topical or intraocular medication.

Locations (1)

Royal Surrey Country Hospital

London, United Kingdom

Key Dates

Start Date

August 2, 2024

Primary Completion Date

March 31, 2025

Completion Date

April 1, 2025

Last Updated

July 1, 2025

Enrollment

ACTUAL participants

Conditions

Wilson Disease

Interventions

Diagnostic procedures

DIAGNOSTIC_TEST

Institutional Registry of Rare Diseases

NCT06573723

Rare DiseasesAmyloidosis+24 more

View study

COMPLETED

The Clinical Study of Botulinum Toxin Type A Injection in the Treatment of Wilson Disease

NCT06762509

Wilson Disease

View study

TERMINATEDPHASE3

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 1, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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The Exploratory Handheld Optical Coherence Tomography Study in Wilson's Disease

Inclusion Criteria

Exclusion Criteria

Institutional Registry of Rare Diseases

The Clinical Study of Botulinum Toxin Type A Injection in the Treatment of Wilson Disease

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