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A Phase I, Open-Label, Dose-Escalation Study to Investigate the Safety of ISTH0036, a 'Next Generation' TGF-β2-Selective Antisense Oligonucleotide, in Subjects With Primary Open-Angle Glaucoma Undergoing Trabeculectomy
Conditions
Interventions
TGF-β2 antisense oligonucleotide
Trabeculectomy
Locations
3
Germany
University Hospital Magdeburg, Ophthalmology
Magdeburg, Germany
Department of Ophthalmology, Johannes-Gutenberg University Mainz
Mainz, Germany
University of Tuebingen, Center of Ophthalmology
Tübingen, Germany
Start Date
April 1, 2015
Primary Completion Date
August 1, 2016
Completion Date
August 1, 2017
Last Updated
February 28, 2018
NCT07390890
NCT07358650
NCT05902871
NCT07076303
NCT06865144
NCT05564091
Lead Sponsor
Isarna Therapeutics GmbH
Data Source & Attribution
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