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Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) for Reducing Medication Burden in Medically Controlled Patients With Ocular Hypertension or Primary Open Angle Glaucoma
This is a prospective, single arm, open label study conducted at a single site to evaluate the efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in reducing medication burden in patients with medically controlled ocular hypertension or primary open angle glaucoma. The study will assess the primary endpoint of reduction in medication count at 6 months compared to baseline. Secondary endpoints include IOP reduction compared to baseline (both percentage and absolute), complete success rate (no increase in IOP without medications), proportion of eyes needing medication at 6 months, and any secondary surgical interventions at 6 months post-DSLT. Participants will undergo DSLT with 120 shots, 400 µm spot size, and 1.8mJ fixed energy delivered at the limbus over 2.4 seconds. Follow-up visits will occur at 1 month, 3 months, and 6 months post-procedure, with IOP measured using a calibrated Goldmann tonometer.
Age
All ages
Sex
ALL
Healthy Volunteers
No
The Eye Institute of West Florida
Largo, Florida, United States
Start Date
February 26, 2026
Primary Completion Date
January 26, 2027
Completion Date
January 26, 2027
Last Updated
February 5, 2026
60
ESTIMATED participants
Voyager DSLT
DEVICE
Lead Sponsor
The Eye Institute of West Florida
Collaborators
NCT05902871
NCT07218796
Data Source & Attribution
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