SIT LESS 3: The Effect of Low Intensity Physical Activity on Insulin Sensitivity, Mood and Cognitive Performance

Exclusion Criteria

• •Reported participation in another biomedical trial which may have an effect on insulin sensitivity one month before the pre-study examination or during the study
• •Blood donation in the past three months
• •Reported participation in night shift work 2 weeks prior to pre-study investigation or during the study. Night work is defined as working between midnight and 6.00 AM.
• •Consumption of \>14 (women) or \> 21 (men) alcoholic units per week
• •Reported dietary habits: medically prescribed diet, slimming diet;
• •Reported weight loss (\>2kg) in the last three months prior to the screening;
• •Not being able to execute at least three (out of four) cognition tests in the training session
• •Not being able to execute the sit less try-out day
• •Being an employee of Unilever or the collaborating research departments in Maastricht University Medical Centre
• •Experimental drug use (during the last 3 months)
• •Use of insulin, oral blood glucose lowering medication (metformin and/or SU-derivatives and/or DPP-IV inhibitors), corticosteroids or vitamin K antagonists in the last 3 months
• •Fasting plasma glucose level \> 6.9 mmol/L
• •Medical conditions which make participation in the study not responsible which will be decided by a medical doctor during screening
• •Other clinically relevant abnormalities in clinical chemistry at screening (to be judged by a medical doctor)
• •Mental or physical disability which interferes with physical activity