Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Boston Scientific Corporation
Prospective, multicenter, single blinded, randomized, controlled, pilot study. Subjects will be randomized to renal denervation treatment or masked renal angiogram procedure (2:1).
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥18 and ≤75 years
OSBP ≥150 mmHg and ≤180 mmHg based on an average of 3 office-based blood pressure measurements
Average 24-hour ASBP ≥135 mmHg and ≤170 mmHg
For each kidney, a main renal artery, with or without accessory renal arteries, with diameter ≥3.0 mm and ≤7.0 mm and length ≥20.0 mm
Agrees to have all study procedures performed, and is competent and willing to provide written, informed consent
You may not be if
Stenosis \>30% or renal artery aneurysm in either renal artery
Fibromuscular dysplasia (FMD)
Known causes of secondary HTN
Type 1 diabetes mellitus
eGFR \<40 mL/min/1.73m2
Known ejection fraction of \<30% or heart failure that required hospitalization in the previous 6 months
Severe valvular heart disease
≥1 episode(s) of orthostatic hypotension not related to medication changes (reduction of SBP of ≥20 mmHg or DBP of ≥10 mmHg within three minutes of standing) coupled with symptoms within the past year or during screening
