Efficacy of Intermittent ThetaBurst Stimulation Compared to 10 Hz Stimulation on Dorsolateral Prefrontal Cortex in Treatment Resistant Major Depressive Disorder: a Double-blind Randomized Study
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Keep this study
Lead
Nantes University Hospital
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18 years to 75 years
Both gender eligible
Volontary and able to give consent
Major depressive episode (MADRS \> 20) single or recurrent
Resistance to at least 2 antidepressants ,
Treated by antidepressant at efficient stable posology since more than 6 weeks
You may not be if
Initiation or modification of antidepressant drug
Neurodegenerative diseas
Bipolar I, II disorder
Schizophrenia, schizoaffective disorder, schizophreniform, delusional disorder, or current psychotic symptoms
Substance abuse in past 15 days
Substance dependence not weaned
Benzodiazepine and any anticonvulsant during rTMS treatment course
ECT failure in medical history
Contra-indication to rTMS and MRI
Pregnancy
Difficulty to obtain informed consent
Clareo Health | Efficacy of Intermittent ThetaBurst Stimulation Compared to 10 Hz Stimulation on Dorsolateral Prefrontal Cortex in Treatment Resistant Major Depressive Disorder: a Double-blind Randomized Study
