Juno Perth Clinical Trial

Exclusion Criteria

• •Subjects not compliant on NIV (ie. \< 4 hr/night)
• •Subjects with severe asthma
• •Subjects who are pregnant
• •Subjects on oxygen therapy (ie. \>4 L/min)
• •Subjects with a tracheostomy
• •Subjects who are acutely ill, medically complicated or who are medically unstable
• •Subjects in whom PAP therapy is otherwise medically contraindicated
• •Subjects who have had surgery of the upper airway, nose, sinus, or middle ear within the previous 90 days
• •Subjects with untreated, non-OSA sleep disorders, including but not limited to; insomnia, periodic limb movement syndrome, or restless legs syndrome.
• •Subjects who require ventilatory support during wakefulness
• •Subjects with the following pre-existing conditions: severe bullous lung disease, recurrent pneumothorax or pneumomediastinum, low blood pressure, cerebrospinal fluid leak, recent cranial surgery or trauma.
• •Subjects with severe developmental delay and who will not be able to follow tasks as instructed in the protocol.
• •Subjects who the investigator believes are unsuitable for inclusion because either:
• •* they do not comprehend English
• •* they are unable or unwilling to provide written informed consent
• •* they are physically unable to comply with the protocol
• •* they are unsuitable to participate in the trial for any other reason in the opinion of the investigator