Pharmacologically Active Constituents of Chocolate and Their Symptomatic Effects in Patients With Idiopathic Parkinson's Disease

Exclusion Criteria

• •Clinical signs for a secondary or atypical Parkinsonian syndrome
• •Treatment with any investigational medical product within 30 days prior to study inclusion
• •Intake of chocolate or other cocoa-containing products within the last 7 days prior to study inclusion (patients can be re-screened after 7 days of abstinence from chocolate and other cocoa-containing products)
• •Known intolerance or allergies against chocolate or other cocoa-containing products
• •Diabetes mellitus and/or impaired glucose tolerance in the medical history
• •Alcohol or drug abuse in the medical history
• •Presence of levodopa-induced motor complications
• •Other neurological, psychiatric or miscellaneous conditions that would significantly impair study participation, medical assessments or the consenting process