Loading clinical trials...
Loading clinical trials...
Despite improvements in analgesic treatment following total knee arthroplasty (TKA) for osteoarthrosis, a substantial part of patients still have severe acute pain after surgery. It has been suggested that preoperative degree of intraarticular inflammation is associated to postoperative degree of pain and level of function. Furthermore it is known, that patients with preoperative inflammation have hyperalgesia and severe movement related pain. The aim of this study is to investigate the effect of a preoperative intraarticular injection of Methylprednisoloneacetate in reducing acute postoperative pain after total knee arthroplasty in patients with signs of severe pre-operative inflammation and pain.
Age
50 - 80 years
Sex
ALL
Healthy Volunteers
No
Gentofte Hospital
Hellerup, Denmark
Start Date
October 1, 2014
Primary Completion Date
March 1, 2016
Completion Date
March 1, 2016
Last Updated
June 6, 2016
48
ACTUAL participants
Methylprednisoloneacetate
DRUG
Lidocaine
DRUG
sodium chloride
OTHER
Lead Sponsor
Rigshospitalet, Denmark
Collaborators
NCT01581450
NCT03450161
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT05016128