Myocardial Hybrid Revascularization Versus Coronary artERy Bypass GraftING for Complex Triple-vessel Disease

Exclusion Criteria

• •Prior PCI or CABG at any time prior to randomization
• •Need for any concomitant cardiac surgery other than CABG (e.g. valve surgery, aortic repair, etc.), or intent that if the patient randomizes to surgery, any cardiac surgical procedure other than isolated CABG will be performed
• •Patients unable to tolerate, obtain or comply with dual antiplatelet therapy for at least one year
• •Patients requiring additional surgery (cardiac or non cardiac) within one year
• •The presence of any clinical or anatomical condition(s) which leads the participating interventional cardiologist to believe that clinical equipoise is not present (i.e. the patient should not be treated by PCI, but rather should be managed with CABG or medical therapy - reasons will be documented)
• •The presence of any clinical or anatomical condition(s) which leads the participating cardiac surgeon to believe that clinical equipoise is not present (i.e. the patient should not be treated by CABG, but rather should be managed with PCI. or medical therapy - reasons will be documented)
• •Non cardiac co-morbidities with life expectancy less than 1 year
• •Other investigational drug or device studies that have not reached their primary endpoint.