Evolocumab in Patients With Multivessel Coronary Disease After Acute Myocardial Infarction: A Target Trial Emulation

Exclusion Criteria

• •Cardiac shock, hemodynamically unstable, or severe heart failure (Killip IV)
• •Any cardiac surgery within 6 weeks prior to screening;
• •Moderate to severe renal dysfunction, defined as an estimated glomerular filtration rate (eGFR) less than 30 mL/min/1.73m\^2 at screening;
• •Contraindication or allergy to iodinated contrast agent;
• •Malignancy except non-melanoma skin cancers, cervical, or breast ductal carcinoma in situ within the last 5 years;
• •Female subject is pregnant or breastfeeding or planning to become pregnant or breastfeed in short term.