Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Memorial Sloan Kettering Cancer Center
With
Cardiff Oncology
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Lung cancer:
For patients participating in Part A (initial testing) and Part B (serial testing):
Patients must have a diagnosis of stage IV lung adenocarcinoma undergoing systemic therapy.
Patients must have had or intend to have EGFR mutation testing (specifically including exon 19 deletions and L858R) performed on their tumor with results available from a CLIA certified laboratory.
≥ 18 years of age
Specific to patients participating in Part B (serial testing):
Patients must be planning to receive cancer care at Memorial-Sloan Kettering.
Patients must have a confirmed EGFR mutant lung cancer (exon 19 deletions and L858R) with molecular testing results available from a CLIA certified laboratory.
Must be within 3 months of their diagnosis of metastatic lung cancer.
Treatment plan should include an EGFR tyrosine kinase inhibitor, but may concurrently be on a therapeutic protocol.
Colorectal Cancer:
For patients participating in Part A (initial testing) and Part B (serial testing):
Patients must have a diagnosis of stage IV colorectal adenocarcinoma undergoing systemic therapy or have recently progressed on therapy including anti-EGFR based therapy.
Patients must have had or intend to have RAS/RAF mutation testing on their tumor with results available from a CLIA certified laboratory. For the patients who recently progressed on anti-EGFR must have tumor tissue molecular analyses preformed (prior to enrolling or a plan to test it at the time of enrollment).
\>18 years of age
Specific to patients participating in Part B (serial testing):
Patients must be planning to receive cancer care at Memorial-Sloan Kettering.
Patients must have a confirmed RAS/RAF mutant colorectal cancer with molecular testing results available from a CLIA certified laboratory.
Must be within 3 months of their diagnosis of metastatic colorectal cancer.
You may not be if
lung cancer and colorectal cancer
Comorbidities that would prohibit or make serial urine collection difficult or impossible
