Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Boehringer Ingelheim
Age
25–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patient is ≥ 25 years of age
Patient is either male or female
Outpatient. Change to inpatient is not allowed during the study period
Blood pressure is measured 3 times or more during the 4-week observation period; the last 2 measurements in the sitting position (intervals between measurements must be less than 4 weeks) are stabilized for both of systolic pressure (within +/- 30 mmHg) and diastolic pressure within +/- 15 mmHg) with the mean exceeding 160 mmHg for systolic and 95 mmHG for diastolic pressure
You may not be if
Patient has severe hypertension (the last 2 measurements in the observation period exceed 120 mmHg in terms of diastolic blood pressure)
Patient has secondary or malignant hypertension
Patient has a history of severe cardiac failure, unstable angina, or myocardial infarction within previous six months
Patient has atrioventricular conduction disturbance, atrial fibrillation or severe arrhythmia
Patient has any symptoms of cerebrovascular disorder
Patient has serious hepatic dysfunction (either GOT (glutamic-oxaloacetic transaminase) or GPT (glutamic-pyruvic transaminase) exceeds 100 U)
Patient has renal dysfunction (serum creatinin ≥ 2.1 mg/dl)
Patient has uncontrolled diabetic (either of the following tests exceeds the specified standards: fasting blood glucose exceeding 151 mg/dl or HbA1c exceeding 8%)
Patient has a history of drug sensitivity to ACE (angiotensin converting enzyme) inhibitors and angiotensin II receptor antagonists
Patient has a history of angioedema due to ACE inhibitors
Patient has hyperkalemia (K exceeding 5.5 mEq/l)
Patient has received enalapril just before the start of observation period
Patient has received treatment with any other investigational drug(s) within three months of the start of observation period
Patients is pregnant, breast-feeding, or possible pregnant, or wants to be pregnant during the study period
Patient has any other condition that the investigator or subinvestigator feels would be inappropriate for the study participation
Clareo Health | BIBR 277 Capsule in Patients With Essential Hypertension
