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COMPLETEDNCT02141880

The Tailgate Study: A Pilot Study Measuring the Impact of Acute Alcohol Intake on Intrahepatic Lipid

College drinking associated with sporting events is characterized by excess alcohol, along with food intake, over the duration of hours has the potential to cause a build up of fat in the liver. Fatty...

Lead sponsor: University of Missouri-Columbia•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Missouri-Columbia

Subjects will participate in a single screening visit and a 24 hours in-patient stay at the clinical research center for treatment and tests. No drugs will be used in this study, however, amounts of alcohol will be consumed to achieve, and maintain a breath alcohol at the legal limit (0.10). The goals are to quantitate the increase in lipogenesis due to acute alcohol/food intake and to determine the effects of acute alcohol/food intake on liver-triglycerides.

Age

21 - 40 years

Sex

MALE

Healthy Volunteers

Yes

Inclusion Criteria

•Men
•Age 21-40
•BMI 25.1-35.0 kg/m2
•Waste girth \< 55 inches
•Nonsmoking
•Moderate consumer of alcohol
•Fasting blood glucose \< 125 mg/dL, alanine transaminase activity \< 40 milliunits/L, plasma triglycerides \< 200 mg/dL
•Sedentary
•Free of metabolic disorders

Exclusion Criteria

•BMI \< 25.1 or \> 35.0 kg/m2
•Waste girth of greater 55 inches
•Use of any tabacco product
•Fasting plasma glucose ≥125 mg/dL, alanine transaminase activity ≥ 40 milliunits/L, plasma triglycerides ≥125 mg/dL
•Physically active
•Diabetes or other diseases that impact blood glucose or lipids
•Fatty liver disease

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 2, 2020Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment25

Start dateJun 2014

Last updatedNov 2, 2020

Condition

Locations shown

University of Missouri

Columbia, Missouri

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 2, 2020Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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