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Real Life Effectiveness of Easyhaler (Orion) | Clinical Trials | Clareo Health

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COMPLETEDNCT02048930

Real Life Effectiveness of Easyhaler (Orion)

The aim of this study is to compare the clinical effectiveness and cost-effectiveness of the Easyhaler® (EH) device and other DPI devices commonly used in the UK in a UK primary care asthma population...

Lead sponsor: Research in Real-Life Ltd•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Research in Real-Life Ltd

Collaborators

Orion Corporation, Orion Pharma

A recent observational study by Price et al carried out using the UK's General Practice Research Database (CPRD) to compare asthma-related outcomes for different inhaled corticosteroid (ICS) inhaler devices, using Easyhaler and dry powder inhalers (DPIs).

Age

6 - 80 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•(1) Aged: 6-80 years - stratified 6-11 years; 12-60 years; ≥61 years to allow paediatrics and adolescent / adult sub analyses; and to allow for the exclusion of elderly (aged 61+) smokers and ex-smokers if required.
•(2) On-going asthma therapy: ≥2 prescriptions for asthma during the outcome period (i.e. ≥1 prescription (for any asthma therapy) in addition to the prescription for ICS at IPD (initiation / step-up/ switch).
•(3) Evidence of active asthma:
•1. Initiation - a diagnostic code for asthma
•2. Step-up / Switch - ≥2 prescriptions for asthma (at least one of which is for ICS) at different points in time during the baseline year PLUS a diagnostic code for asthma.
•(4) Have at least one year of up-to-standard (UTS) baseline data and at least one year of UTS outcome data (following the IPD).

Exclusion Criteria

•Patients will be excluded from the analysis if they have:
•(1) Had a COPD read code at any time; and/or
•(2) Had any chronic respiratory disease, except asthma, at any time; and/or
•(3) Patients on maintenance oral steroids during baseline year; and/or
•(4) Multiple ICS prescriptions at IPD.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 29, 2014Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment24,003

Start dateSep 2012

Last updatedJan 29, 2014

Condition

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 29, 2014Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions