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Phase 3 Study of EBI-005 in Dry Eye Disease | Clinical Trials | Clareo Health

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COMPLETEDPhase 3NCT01998802

Phase 3 Study of EBI-005 in Dry Eye Disease

This is a phase III double-masked, randomized, controlled study evaluating the efficacy of EBI-005 as compared to vehicle given as a topical ophthalmic solution in each eye to subjects with moderate t...

Lead sponsor: Eleven Biotherapeutics•45 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Eleven Biotherapeutics

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Give written informed consent and any authorizations required by local law (e.g., Protected Health Information waiver) prior to performing any study procedures;
•Are ≥ 18 years of age;
•Are willing and able to follow instructions and can be present for the required study visits for the duration of the study;
•Have a history of dry eye disease (DED) in both eyes supported by a previous clinical diagnosis
•Have normal lid anatomy.
•If female and of child bearing potential, she must not be not pregnant or lactating and not sexually active (abstinent) within 14 days prior to Visit 1

Exclusion Criteria

•Have signs of infection (i.e., fever or current treatment with antibiotics)
•Have been exposed to an investigational drug/device within the preceding 30 days
•Be an employee of the site that is directly involved in the management, administration, or support of the study, or be an immediate family member of the same
•Be unwilling to or unable to comply with the study

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 11, 2015Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE3

Enrollment670

Start dateJan 2014

Last updatedJun 11, 2015

Condition

Dry Eye Disease (DED)

Locations shown

Investigational Site

Chandler, Arizona

Investigational Site

Mesa, Arizona

Investigational Site

Little Rock, Arkansas

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 11, 2015Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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