Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Southampton
Age
18–50
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Confirmed diagnosis of asthma
Step one of treatment by GINA (2006) guidelines
baseline FEV1 \>80% predicted
You may not be if
current smoker
ex smoker who quit \<1 year prior to study and pack history \>10 pack years
current use of aspirin or other anticoagulant medication
Diagnosis or documented history of bronchopulmonary aspergillosis or uncontrolled infections
Any clinically significant cardiopulmonary abnormalities not related to pre-existing asthma
Past or present tuberculosis, systemic lupus erythematosis or multiple sclerosis
Any clinically significant neurological, renal, endocrine, gastrointestinal, hepatic or haematological abnormalities uncontrolled with standard treatment
History of psychiatric, medical or surgical disorders that may interfere with study
Clinical history suggestive of respiratory infection in month preceding study
Alcohol or recreational drug abuse
Diagnosis of immunodeficiency requiring treatment
Treatment with immunomodulators (inhaled corticosteroids in two months or oral corticosteroids in six months prior to study)
Ongoing allergen desensitisation therapy
Regular use of sedatives, hypnotics, tranquillisers
Positive hepatitis viral antigens or antibodies
Blood donation within 3 months of the study
Live immunisation \<4 wks prior to study
Inability to understand directions for study assessment
Inability to be contacted in case of emergency
Participation in another study at the same time or within a prior 3-month period
Clareo Health | Effect of Clopidogrel on Allergen Challenge in Asthma
