Upper or lower respiratory tract infection within 4 weeks.
Exacerbation (requiring oral corticosteroids or hospitalization) within 3 months.
Current smoker or former smoker less than 6 months or total lifetime smoking history greater than 10 pack-years.
Intolerance to salbutamol.
Intolerance to tiotropium (or any other atropine-derived compound).
Intolerance to one of the ingredients of the study product
Severe hepatic impairment, moderate to severe renal impairment, epilepsy, narrow angle glaucoma, gastrointestinal obstruction, moderate to severe prostatic hypertrophy, bladder neck obstruction.
Any acute or chronic disease that will not allow the participation in the study, in the judgement of the investigator.
