Effect of Nutrition on Bone Metabolism as Assessed by 41Ca

Exclusion Criteria

• •1. Participation in any clinical trial including blood sampling and/or administration of substances up to 90 days before Day 01 of this study
• •2. Participation in any non-invasive clinical trial up to 30 days before Day 01 of this study, including no blood sampling and/or oral, intravenous, inhalatory administration of substances
• •3. Having a history of medical or surgical events that may significantly affect the study outcome, including cardiovascular disease or hypertension and gastrointestinal disease
• •4. Prescribed medication, including hormone replacement therapy (within 6 months before start of the study) and anticoagulant medication.
• •5. Reported intolerance for dairy products
• •6. Not willing to stop the use of Boerenkarnemelk and cheese of the following Dutch brands: Emmenthaler, Gruyere, Leer/Maasdammer
• •7. Alcohol consumption \> 21 units/week
• •8. Not willing to stop use of supplements containing minerals or vitamins
• •9. Reported unexplained weight loss or gain of \> 2 kg in the month prior to the pre-study screening
• •10. Reported slimming or medically prescribed diet
• •11. Reported vegan, vegetarian or macrobiotic
• •12. Recent blood donation (\<1 month prior to the start of the study)
• •13. Not willing to give up blood donation during the study.
• •14. Personnel of TNO Quality of Life, their partner and their first and second degree relatives
• •15. Not having a general practitioner
• •16. Not willing to accept information-transfer concerning participation in the study, or information regarding her health, like laboratory results, findings at anamnesis or physical examination and eventual adverse events to and from her general practitioner.