Treatment of Suicidal Ideation With Intravenous Ketamine Infusion

Exclusion Criteria

• •1. Pregnant or lactating; women of reproductive potential must have a negative urine pregnancy test (urine dipstick method)
• •2. Post-Partum state : defined as being within 2 months of delivery or miscarriage
• •3. Homicide risk as determined by clinical interview
• •4. Treatment with any medication known to specifically target the glutamate-NMDA receptor system (ie lamotrigine, acamprosate, memantine, riluzole or lithium)
• •5. Any known hypersensitivity or serious adverse effect associated with ketamine treatment.
• •6. Any clinically significant medical condition or therapy that would preclude treatment with ketamine, to include recent myocardial infarction or unstable angina
• •7. Medically unstable, including acute withdrawal from alcohol or benzodiazepines requiring the use of benzodiazepine treatment.
• •8. Any of the following DSM-IV diagnoses or categories:
• •* Any current psychosis or history of a non-mood psychotic disorder (e.g., schizophrenia)
• •* Currently in a manic or mixed episode
• •* Current use (defined by urine dipstick test) or abuse of hallucinogenic drugs (except marijuana) such as phencyclidine
• •* Any dissociative disorder
• •* Any pervasive developmental disorder (e.g., autism)
• •* A cognitive disorder (e.g., Alzheimer's Disease)
• •* Cluster A personality disorder (e.g., schizoid or schizotypal); note that cluster B and C personality disorders may be included
• •* Any eating disorder