The Effect of Continuous Positive Airway Pressure on Diastolic Function in Patients With Obstructive Sleep Apnea

Exclusion Criteria

• •Age \< 20 years-old
• •Left ventricular dysfunction (LVEF\<50%) or structural heart disease on transthoracic echocardiography
• •Diabetes mellitus
• •Significant cardiac valvular disease (≥moderate)
• •Severe hypertension (\>180/110mmHg)
• •Moderate or severe kidney disease (eGFR \< 60 mL/min )
• •Clinically significant liver disease
• •History of coronary artery disease
• •malignancy or autoimmune disease
• •Acute/chronic infection status
• •Pregnant status
• •Patients taking anxiolytics or sedatives