Oral Vinorelbine as Induction Chemotherapy Followed Concomitant Chemoradiotherapy

Exclusion Criteria

• •stages I, II, IIIA (excepted N2), IIIB with pleural effucion and stage IV,
• •pregnant or breastfeeding women. Women of Childbearing Age: Women of childbearing potential should take reliable contraceptive measures
• •Symptomatic Neuropathy \> grade 1,
• •associated Pathology and/or not controled diseases(cardiac insuficiency, myocardial infarction within 3 months before the inclusion ; hypertension, arythmia or uncontroled hypercalcémia; infection requiering iv antibiotic administration within 2 weeks before inculion),
• •other associated cancer with the exception of cervical carcinoma in situ or skin cancer baso-cellular correctely treated,
• •Previous treatment with an other antineoplasic,
• •Known hypersensibility to drugs with a similar chemical structure ti this studied.
• •important malabsorbtion syndrom or disease of gastro-intestinal track,
• •Participation to another clinical trial within 30 days before inclusion