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Benefits Study of Respiratory-gated PET Acquisition in Lung Disease | Clinical Trials | Clareo Health

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Benefits Study of Respiratory-gated PET Acquisition in Lung Disease

Benefits Study of a Respiratory Gating Protocol for Positron Emission Tomography: Application on the Lungs

NCT01812031•Centre Hospitalier Universitaire, Amiens

Summary

Fluorodeoxyglucose (FDG) positron emission tomography (PET) is now widely used for cancer imaging purpose, notably for preoperative work-up. It aims at visualizing organs metabolism. In case of cancer, metabolism is, classically, increased and some hot spots are visible on PET images. Because of respiratory motion some lung tumours (especially the smallest ones) can be falsely interpreted by the clinician. The investigators developed a respiratory-gated PET method in order to reduce the motion issue. The investigators designed a study to investigate its effect on lung cancer (primary or metastasis) to check if it improves the sensitivity/specificity of PET imaging of the lungs. To that aim, patients presenting a lung nodule on a CT examination can be proposed to participate this study. After the standard PET acquisition (acquired in free-breathing), an additional 10 minutes respiratory-gated PET acquisition is performed without additional injection. After that, a breath-hold (\~10s) CT is performed.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•patient has one or more lung lesion(s) less than 35 mm visible on a CT image
•age : over 18 years
•patients gave their written informed consent

Exclusion Criteria

•pregnancy
•patient has at least one lesion more than 35 mm in its great axis

Locations (1)

CHU Amiens

Amiens, Picardie, France

Key Dates

Start Date

August 1, 2009

Primary Completion Date

February 1, 2013

Completion Date

February 1, 2015

Last Updated

September 19, 2025

Enrollment

103

ACTUAL participants

Conditions

Lung CancerNon Small Cell Lung CancerChronic Obstructive Pulmonary Disease

Interventions

medical imaging

OTHER

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 19, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Benefits Study of Respiratory-gated PET Acquisition in Lung Disease

Inclusion Criteria

Exclusion Criteria

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

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