The Efficacy and Safety of Electronic Cigarettes: a 5-year Follow-up Study

Inclusion Criteria

• •resident into the Abruzzo and Lazio Region
• •aged between 30 and 75 years;
• •smoker of e-cigarettes (inhaling at least 50 puffs per week) containing nicotine since six or more months (E-cigarettes only Group);
• •smoker of at least one traditional cigarette per day since six or more months (Traditional cigarettes only Group);
• •smoker of both electronic and traditional cigarettes (at least one per day) since six or more months (Mixed Group).